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Chapter 79 Parathyroid Hormone, Calcitonin, Calcium and Phosphate Metabolism, Vitamin D, Bone, and Teeth
Complete Chapter Questions And Answers
Sample Questions
1. A man consumes a high Ca2+ meal. Which of the following would be an appropriate compensatory response to the postprandial changes in plasma [Ca2+] concentration?
A. Increased calcitonin secretion
B. Increased formation of 1,25-(OH)2D3
C. Increased osteoclastic activity
D. Increased renal Ca2+ reabsorption
E. Increased osteocytic osteolysis
ANS: A
2. Which of the following is not a direct effect of PTH?
A. Increased renal Ca2+ reabsorption
B. Decreased renal phosphate reabsorption
C. Increased intestinal Ca2+ and phosphate absorption
D. Increased Ca2+ and phosphate resorption from bone
E. Increased renal production of 1,25-(OH)2D3
ANS: C
3. Which of the following would cause the most rapid increase in free ionized plasma Ca2+ concentration?
A. Increased osteocytic osteolysis
B. Increased osteoclastic activity
C. Increased formation of 1,25-(OH)2D3
D. Increased renal Ca2+ reabsorption
E. Increased intestinal Ca2+ absorption
ANS: A
Questions 4-6: Match each of the following patients in questions 4 and 6 with the following physiological changes.
Plasma [PTH] Plasma [1,25-(OH)2D3] Plasma [Phosphate]
A.
B.
C.
D.
E.
4. Most patients with rickets.
ANS: C
6. Most patients with osteomalacia.
ANS: C
7. A lethargic 60-year-old woman has complained of fatigue, depression, weakness, and constipation for several years. She has been taking several over-the-counter vitamin preparations for years. Abdominal x-rays reveal kidney stones and urine calcium is high. Her PTH level is low. Which of the following is the most likely cause of her symptoms?
A. Vitamin D excess
B. Primary hyperparathyroidism
C. Secondary hyperparathyroidism
D. Surgical hypoparathyroidism
E. Poor exposure to sunlight
ANS: A
8. Which of the following would not be a prominent response to PTH?
A. Increased Ca2+ reabsorption in the proximal tubule
B. Increased osteocytic osteolysis
C. Increased osteoclastic activity
D. Increased formation of 1,25-(OH)2D3 in the proximal tubule
E. Decreased phosphate reabsorption in the proximal tubule
ANS: A
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