Chapter 54 Drug Therapy for Depression and Mood Stabilization

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Chapter 54  Drug Therapy for Depression and Mood Stabilization

 

 

Complete chapter Questions And Answers
 

Sample Questions

 

 

1. A woman has a history of long periods of depression interspersed with hypomanic episodes. What mood disorder is the patient most likely suffering from?

  1. A)  Bipolar disorder type I
  2. B)  Bipolar disorder type II
  3. C)  Situational depression
  4. D)  Coping disorder

Ans: B Feedback:

Bipolar disorder type II is characterized by episodes of major depression plus hypomanic episodes and occurs more frequently in women. Bipolar disorder type I is characterized by episodes of major depression plus mania and occurs equally in men and women. Situation depression lasts a shorter amount of time and is related to life events. A coping disorder is not related to hypomania.

2. A patient is admitted for assessment because of his history of inappropriately flamboyant and extroverted behavior coupled with risk-taking behaviors. The wife states he has also had periods of major depression but refuses to seek help. From what mood disorder is the patient most likely suffering?

  1. A)  Schizophrenia
  2. B)  Depression
  3. C)  Bipolar disorder type I
  4. D)  Bipolar disorder type II

Ans: C
Feedback:
Bipolar disorder type I is characterized by episodes of major depression plus mania and occurs equally in men and women. Schizophrenia results from abnormal brain synapses and includes a wide variety of diseases. Depression is a mood disorder, but does not exhibit periods of mania. Bipolar disorder type II is characterized by episodes of major depression plus hypomanic episodes and occurs more frequently in women.

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3. A patient suffers from depression and states feelings of gloom and inability to perform the activities of daily living. The normal function of which neurotransmitter is most likely impaired?

  1. A)  Acetylcholine
  2. B)  Epinephrine
  3. C)  Insulin
  4. D)  Serotonin

Ans: D
Feedback:
Serotonin helps regulate several behaviors that are disturbed in depression. Acetylcholine is a neurotransmitter with action in the cardiac and skeletal muscle. Acetylcholine has a limited impact in depression. Epinephrine is not associated with depression, though norepinephrine is implicated. Insulin is released by the pancreas to regulate blood sugar.

4. A patient has been taking a selective serotonin reuptake inhibitor for the treatment of depression. Which of the following represents the action of the medication?

  1. A)  Selective serotonin reuptake inhibitors block GABA.
  2. B)  Selective serotonin reuptake inhibitors prevent serotonin from being reabsorbed.
  3. C)  Selective serotonin reuptake inhibitors increase serotonin synthesis.
  4. D)  Selective serotonin reuptake inhibitors increase the number of serotonin binding sites.

Ans: B

Feedback:

Fluoxetine and the other SSRIs block the reabsorption of the neurotransmitter serotonin in the brain. This helps elevate mood. SSRIs do not increase serotonin synthesis or the number of binding sites. They do not influence the role of GABA.

5. An 8-year-old child is being seen in the clinic. The mother states he suffers from bed-wetting at least four times per week. What medication is effective in treating enuresis in children?

  1. A)  Amitriptyline (Elavil)
  2. B)  Duloxetine (Cymbalta)
  3. C)  Imipramine (Tofranil)
  4. D)  Venlafaxine (Effexor)

Ans: C

Feedback:

Imipramine (Tofranil) is approved for treating childhood enuresis in children older than 6 years. Amitriptyline (Elavil) is a tricyclic antidepressant but is not used for childhood enuresis. Duloxetine (Cymbalta) is a serotonin–norepinephrine reuptake inhibitor that is used for depression. Venlafaxine (Effexor) is a serotonin–norepinephrine reuptake inhibitor that is used for depression.

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