Chapter 40 Drug Therapy for Hyperthyroidism and Hypothyroidism


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Chapter 40  Drug Therapy for Hyperthyroidism and Hypothyroidism



Complete chapter Questions And Answers

Sample Questions



1. A child is born with cretinism. What element was lacking in the mother’s diet during pregnancy?

  1. A)  Potassium
  2. B)  Iodine
  3. C)  Sodium
  4. D)  Magnesium

Ans: B
Cretinism is uncommon in the United States but may occur with a lack of iodine in the mother’s diet. A lack of potassium, sodium, and magnesium in the mother’s diet will not cause cretinism.

2. A patient suffers from hyponatremia, hypoglycemia, and lactic acidosis. What condition is most consistent with this clinical presentation?

  1. A)  Myxedema coma
  2. B)  Psychotic depression
  3. C)  Cretinism
  4. D)  Congenital hypothyroidism

Ans: A
Myxedema coma is severe, life-threatening hypothyroidism characterized by coma, hypothermia, cardiovascular collapse, hypoventilation, and severe metabolic disorders, such as hyponatremia, hypoglycemia, and lactic acidosis.

3. A woman is started on propylthiouracil (PTU). What is the primary mode of action for propylthiouracil?

  1. A)  Destroys part of the thyroid gland
  2. B)  Inhibits production of thyroid hormone
  3. C)  Suppresses the anterior pituitary hormones
  4. D)  Stimulates the thyroid cells

Ans: B Feedback:

The thioamide drugs inhibit synthesis of thyroid hormone. Iodine preparations inhibit the release of thyroid hormones and cause them to be stored within the thyroid gland. Propylthiouracil does not destroy part of the thyroid gland. Propylthiouracil does not suppress the anterior pituitary hormones. Propylthiouracil does not sedate the central nervous system or suppress the cardiac output.

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4. A patient with hypothyroidism is started on levothyroxine (Synthroid). What should the patient be taught regarding medication administration in the home setting?

  1. A)  Take medication with milk or food.
  2. B)  Do not exercise with the medication.
  3. C)  Take the medication on an empty stomach.
  4. D)  Levothyroxine has a short half-life.

Ans: C Feedback:

Levothyroxine (Synthroid) should be taken on an empty stomach to increase absorption. The medication should not be taken with food. Exercise has no effect on the administration of the medication. Levothyroxine has a long half-life of about 6 to 7 days.

5. A 5-year-old child is diagnosed with hypothyroidism. What will the patient likely develop if the condition is left untreated?

  1. A)  Mental retardation
  2. B)  Renal dysfunction
  3. C)  An immune disorder
  4. D)  Paralytic ileus

Ans: A Feedback:

If cretinism is untreated until the child is several months old, permanent mental retardation is likely to result. The patient will not suffer from renal dysfunction, an immune disorder, or paralytic ileus.

6. A patient has been diagnosed with myxedema. She currently takes ibuprofen (Motrin) for knee pain. For what is this patient at increased risk?

  1. A)  Nephrotoxicity
  2. B)  Pulmonary congestion
  3. C)  Tachycardia
  4. D)  Apnea

Ans: A Feedback:

A patient diagnosed with myxedema cannot metabolize and excrete drugs, so she is at an increased risk of developing nephrotoxicity. Pulmonary congestion, tachycardia, and apnea are not adverse effects related to myxedema or the administration of ibuprofen (Motrin).

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