Chapter 26 Cholinergic Drugs

1. Which of the following are true about the enzyme acetylcholinesterase? Select all that apply:

1. A)  Acetylcholinesterase makes the parasympathetic nervous system function differently.
2. B)  Acetylcholinesterase inactivates the neurotransmitter serotonin.
3. C)  Acetylcholinesterase activates the neurotransmitter acetylcholine.
4. D)  Acetylcholinesterase inactivates the neurotransmitter norepinephrine.
5. E)  Acetylcholinesterase activity results in the prevention of nerve synapses to

   continue nerve impulses.

   2. Which of the following medical conditions can be treated with cholinergic drugs? Select all that apply:

1. A)  Urinary retention
2. B)  Overactive bladder
3. C)  Myasthenia gravis
4. D)  Parkinson’s disease
5. E)  Graves’ disease

   3. The nurse should alert a client to which of the following adverse effects of pilocarpine (Pilopine) ophthalmic drops? Select all that apply:

1. A)  Nausea
2. B)  Headache
3. C)  Nasal congestion
4. D)  Decreased visual acuity
5. E)  Decreased auditory acuity

   4. A nurse should alert a client to which of the following adverse effects of pyridostigmine (Mestinon)? Select all that apply:

1. A)  Constipation
2. B)  Nausea
3. C)  Dry mouth
4. D)  Skin flushing
5. E)  Muscle rigidity

5. A physician orders guanidine 15 mg/kg/day by mouth in fourdivided doses for a client with Eaton-Lambert disease. If the client weighs 147 lbs, how many milligrams will the nurse need to administer to the client daily?
6. If a client is to receive 1000 mg/day of guanidine per day in four divided doses, how many tablets should the nurse administer to the client at each dose if the tablets are 125 mg each?