Chapter 10 Drug Therapy- Immunizations


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Chapter 10  Drug Therapy- Immunizations



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Sample Questions



1. An infant is being administered an immunization. Which of the following provides an accurate description of an immunization?

  1. A)  It should be administered to a pregnant woman prior to the infant’s birth.
  2. B)  It is the administration of an antigen for an antibody response.
  3. C)  It produces many adverse reactions, particularly autism, in the infant.
  4. D)  It protects the infant from exposure to infectious antibodies.

Ans: B Feedback:

Immunization involves administration of an antigen to induce antibody formation. Live, attenuated vaccines should not be administered to the pregnant woman. There are limited adverse effects associated with immunization. The immunization protects the infant from infectious antigens, producing an antibody response. It does not protect from antibodies.

2. A patient is scheduled to receive an immunization. In which of the following patients may the administration of a live vaccine be contraindicated?

  1. A)  Patient with renal insufficiency
  2. B)  Patient with hepatic failure
  3. C)  Patient taking steroid therapy
  4. D)  Patient over the age of 65 years

Ans: C
Patients receiving a systemic corticosteroid in high doses (e.g., prednisone 20 mg or equivalent daily) or for longer than 2 weeks should wait at least 3 months before receiving a live-virus vaccine. No evidence supports withholding immunizations related to renal insufficiency or hepatic failure. Patients over the age of 65 should receive immunizations as needed to protect from infectious disease.

3. A patient is to be administered an immunization. The serum contains aluminum phosphate. What route is most appropriate to administer this immunization?

  1. A)  Intramuscularly
  2. B)  Subcutaneously
  3. C)  Intravenously
  4. D)  Orally

Ans: A
Products containing aluminum should be given intramuscularly only because they cannot be given intravenously and greater tissue irritation occurs with subcutaneous injections. Immunizations containing aluminum are not administered orally.

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4. A patient has received a rubella immunization. The patient was unaware that she was pregnant. What risk is associated with the administration of the rubella immunization in this patient?

  1. A)  Risk of development of the disease in the newborn
  2. B)  Risk of low infant birth weight
  3. C)  Risk of preterm labor
  4. D)  Risk of birth defects

Ans: D


Rubella during the first trimester of pregnancy is associated with a high incidence of birth defects in the newborn. Rubella is not associated with the development of disease. Rubella is not associated with low birth weight or preterm labor.

5. The college health nurse is providing health education for freshmen. Which of the following pieces of information about immunizations is applicable to individuals of this age group?

  1. A)  The oral polio should be updated.
  2. B)  The yearly administration of flu vaccine is recommended.
  3. C)  The tetanus toxoid must be within 2 years.
  4. D)  The administration of hepatitis A vaccine is mandatory.

Ans: B
An annual flu vaccine is recommended for all adults. The administration of oral polio will not need to be updated in this population. The administration of tetanus toxoid should be every 10 years. HAV vaccination is not mandatory.

6. A nursing student is scheduled to receive the hepatitis B series. What type of immunity will this immunization provide?

  1. A)  Active immunity
  2. B)  Passive immunity
  3. C)  Innate immunity
  4. D)  Natural immunity

Ans: B Feedback:

The hepatitis B series produces passive immunity. Passive immunity occurs when antibodies are formed by the immune system of another person or animal and transferred to the host. Active immunity is produced by the person’s own immune system in response to a disease caused by a specific antigen or administration of an antigen from a source outside the body, usually by injection. Innate or natural immunity, which is not produced by the immune system, includes the general protective mechanisms.

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