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Sample Questions Posted Below
Craft, Gordon: Understanding Pathophysiology, 2nd Edition
Chapter 05: Genes
Test Bank
MULTIPLE CHOICE
1. An ordered photographic display of a set of chromosomes from a single cell is a/n:
a. metaphase spread.
b. autosomal spread.
c. karyotype.
d. anaphase spread.
ANS: C REF: p 74
2. The phase of the cell cycle during which the cell prepares for division is referred to as:
a. interphase.
b. telophase.
c. prophase.
d. M phase.
ANS: A REF: p 75
3. Cell chromosomes are duplicated during:
a. anaphase.
b. the S phase.
c. interphase.
d. the M phase.
ANS: B REF: p 75
4. The phase of the cell cycle during which each pair of chromosomes are pulled apart is
referred to as:
a. anaphase.
b. telophase.
c. prophase.
d. metaphase.
ANS: A REF: p 76
5. Which of the following is NOT a phase of mitosis?
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a. anaphase
b. telophase
c. interphase
d. metaphase
ANS: C REF: p 75
6. During which phase of the cell cycle does a cell produce additional organelles and
cytoplasm?
a. G0
b. G1
c. S
d. G2
ANS: B REF: p 75
7. Human sperm cells contain ____ chromosomes:
a. 22
b. 23
c. 44
d. 46
ANS: B REF: p 75
8. The basic components of DNA are:
a. pentose sugars and four phosphate bases.
b. a phosphate molecule, deoxyribose and four nitrogenous bases.
c. adenine, guanine and purine.
d. codons, oxygen and cytosine.
ANS: B REF: p 77
9. Which of the following checkpoints determines that chromosomes are intact before
allowing the cycle to proceed to mitosis?
a. G1/S
b. G2/S
c. G2/M
d. final phase M
ANS: C REF: p 77
© 2015 Elsevier Australia.Test Bank
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10. The base components of DNA are:
a. b. c. d. A, G, C and U.
U, G, C and T.
A, G, C and T.
X, XX, XY and YY.
ANS: C REF: p 77
11. A DNA strand has a region with the sequence ATCGGATC. Which of the following
would be a complementary strand?
a. CGATACGT
b. TAGCCTAG
c. TUGCCTUG
d. UAGCCUAG
ANS: B REF: p 78
12. When considering how nitrogenous bases pair to form a double helix, which of the
following bases will pair with cytosine?
a. uracil
b. thymine
c. adenine
d. guanine
ANS: D REF: p 78
13. The process by which RNA directs the synthesis of protein is called:
a. termination.
b. transcription.
c. promotion.
d. translation.
ANS: D REF: p 79
14. The process by which DNA is copied into messenger RNA is called:
a. termination.
b. transcription.
c. promotion.
d. translation.
ANS: B REF: p 79
© 2015 Elsevier Australia.Test Bank
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15. A section of DNA has the following sequence: AACTGTC. The complimentary
mRNA for this section of DNA would be:
a. UUGACAG
b. TTGACAG
c. TTGUCUG
d. CCAGTGA
ANS: A REF: p 79
16. Which of the following types of RNA forms a DNA template?
a. tRNA
b. mRNA
c. rRNA
d dRNA
ANS: B REF: p 79
17. The term ‘allele’ refers to:
a. b. c. d. a tangled mass of DNA.
the location of chromosomes in a cell.
the location of genes on a chromosome.
an alternative form of a gene at a specific location.
ANS: D REF: p 80
18. An individual has two identical copies of an allele at a given locus. This person would
be _____ for that particular allele.
a. homozygous
b. heterozygous
c. phenotypic
d. genotypic
ANS: A REF: p 81
19. An individual has two different copies of an allele at a given locus. This person would
be _____ for that particular allele.
a. homozygous
b. heterozygous
c. phenotypic
d. genotypic
© 2015 Elsevier Australia.Test Bank
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ANS: B REF: p 81
20. The phenotype of an individual:
a. is the genetic composition of the individual.
b. is fixed at conception.
c. remains constant throughout life.
d. comprises the characteristics and features displayed by the individual.
ANS: D REF: p 81
21. The genotype of an individual:
a. may be affected by the environment.
b. may change throughout life.
c. remains constant throughout life.
d. comprises the characteristics and features displayed by the individual.
ANS: C REF: p 81
22. A couple has three offspring: one child with a dominant disease trait and two who are
normal. The father is affected by the disease, but the mother does not have the disease
gene. What is the risk of this disease for their next child?
a. 50%
b. 33%
c. 25%
d. impossible to determine
ANS: A REF: p 82
23. Blue eye colour is recessive, whereas brown eye colour is a dominant trait. A child is
born with blue eyes (bb). The child’s mother has blue eyes and the father has brown eyes.
Which of the following represents the father?
a. bb
b. Bb
c. BB
d. Bb or BB
ANS: B REF: p 82
24. Freckles are determined by a dominant gene. A mother has freckles and the father
does not. Their child also has freckles. The mother’s genotype would be
a. f/f
© 2015 Elsevier Australia.Test Bank
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b. F/f
c. F/F
d. F/F or F/f
ANS: D REF: p 82
25. Freckles are determined by a dominant gene. A mother has freckles and the father
does not. Their child also has freckles. The child’s genotype would be
a. f/f
b. F/f
c. F/F
d. F/F or F/f
ANS: B REF: p 82
26. If two copies of an allele are required for its effect to be seen, the allele is:
a. dominant.
b. codominant.
c. recessive.
d. sex-linked.
ANS: C REF: p 81
27. The ABO blood groups are an example of:
a. dominant traits.
b. codominant traits.
c. recessive traits.
d. sex-linked traits.
ANS: B REF: p 83
28. A father has type O blood and the mother’s genotype is iA/iO. What percentage of their
offspring will have type A blood?
a. 25%
b. 50%
c. 75%
d. 100%
ANS: B REF: p 83
29. A father has type O blood and the mother’s genotype is iA/iA. What percentage of their
offspring will have type A blood?
© 2015 Elsevier Australia.Test Bank
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a. 25%
b. 50%
c. 75%
d. 100%
ANS: D REF: p 83
30. A mother has type AB blood and the father’s genotype is iO/iO. What percentage of
their offspring will have type B blood?
a. 25%
b. 50%
c. 75%
d. 100%
ANS: B REF: p 83
31. Which is the rarest blood type?
a. A
b. B
c. AB
d. O
ANS: C REF: p 84
32. Which is the most common blood type in the Australian population?
a. A
b. B
c. AB
d. O
ANS: D REF: p 84
33. The test that screens newborns for more than 30 inherited disorders is called the:
a. Guthrie test.
b. PKU test.
c. codominance test.
d. Punnett test.
ANS: A REF: p 84
34. Phenylketonuria:
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a. b. c. d. causes irreversible mental retardation in untreated children.
is a test that screens for inherited disorders in newborns.
is a method of predicting the likelihood of an individual inheriting a particular
trait.
occurs in every one in 800 babies.
ANS: A REF: p 84
© 2015 Elsevier Australia.
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