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Pharmacotherapeutics for Advanced Practice 4th Edition By Virginia – Test Bank

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Chapter3.ImpactofDrugInteractionsandAdverseEventsonTherapeutics

 

MULTIPLECHOICE

 

  1. Whichofthefollowingpatientswouldbeathigherriskofexperiencingadversedrugreactions(ADRs):
    1. A32-year-oldmale
    2. A22-year-oldfemale
    3. A3-month-oldfemale
    4. A48-year-oldmale

ANS:C                      PTS:1

 

  1. InfantsandyoungchildrenareathigherriskofADRsdueto:
    1. Immaturerenalfunctioninschool-agechildren
    2. Lackofsafetyandefficacystudiesinthepediatricpopulation
    3. Children’sskinbeingthickerthanadults,requiringhigherdosagesoftopicalmedication
    4. Infantboyshavingahigherproportionofmusclemass,leadingtoahighervolumeofdistribution

ANS:B                      PTS:1

 

  1. TheelderlyareathighriskofADRsdueto:
    1. Havinggreatermusclemassthanyoungeradults,leadingtohighervolumeofdistribution
    2. Theextensivestudiesthathavebeenconductedondrugsafetyinthisagegroup
    3. Theblood-brainbarrierbeinglesspermeable,requiringhigherdosestoachievetherapeuticeffect
    4. Age-relateddecreaseinrenalfunction

ANS:D                      PTS:1

 

  1. Thetypeofadversedrugreactionthatistheresultofanunwantedbutotherwisenormalpharmacologicalactionofadruggivenintheusualtherapeuticdosesis
    1. TypeA
    2. TypeB
    3. TypeC
    4. TypeD

ANS:A                      PTS:1

 

  1. DigoxinmaycauseaTypeAadversedrugreactiondueto:
    1. Idiosyncraticeffects
    2. Itsnarrowtherapeuticindex
    3. Beingateratogen
    4. Beingacarcinogen

ANS:B                      PTS:1

 

  1. Changesintheindividualpharmacokineticparametersofadsorption,distribution,oreliminationmayresultinhighconcentrationsofthedruginthebody,leadingtowhichtypeofadversedrugreaction?
    1. TypeA
    2. TypeC
    3. TypeD
    4. TypeE

ANS:A                      PTS:1

 

  1. AccordingtotheWorldHealthOrganizationClassification,TypeBadversereactionsare:
    1. Whenadrugisateratogen
    2. Whenadrugiscarcinogenic
    3. AdelayedADR,suchasrenalfailure
    4. Anallergicoridiosyncraticresponse

ANS:D                      PTS:1

 

  1. SarahdevelopedarashafterusingatopicalThisisaType allergicdrugreaction.
    1. I
    2. II
    3. III
    4. IV

ANS:D                      PTS:1

 

  1. ApatientmaydevelopneutropeniafromusingtopicalSilvadeneNeutropeniaisa(n):
    1. Cytotoxichypersensitivityreaction
    2. Immunecomplexhypersensitivity
    3. Immediatehypersensitivityreaction
    4. Delayedhypersensitivityreaction

ANS:A                      PTS:1

 

  1. Anaphylacticshockisa:
    1. TypeIreaction,calledimmediatehypersensitivityreaction
    2. TypeIIreaction,calledcytotoxichypersensitivityreaction
    3. TypeIIIallergicreaction,calledimmunecomplexhypersensitivity
    4. TypeIVallergicreaction,calleddelayedhypersensitivityreaction

ANS:A                      PTS:1

 

  1. Jameshashypothalamic-pituitary-adrenalaxissuppressionfromchronicprednisone(acorticosteroid)Heisatriskforwhattypeofadversedrugreaction?
    1. TypeB
    2. TypeC
    3. TypeE
    4. TypeF

ANS:B                      PTS:1

 

  1. Thetreatmentforapatientwhoexperienceshypothalamic-pituitary-adrenalaxissuppressionwhiletakingthecorticosteroidprednisone,aTypeCadversedrugreaction,isto:
    1. Immediatelydiscontinuetheprednisone
    2. Administerepinephrine
    3. Slowlytaperthepatientoffoftheprednisone
    4. Monitorforlong-termeffects,suchascancer

ANS:C                      PTS:1

 

  1. TheACEinhibitorlisinoprilTeratogenscauseType adversedrugreaction.
    1. A
    2. B
    3. C
    4. D

ANS:D                      PTS:1

 

  1. CardiacdefectsareaknownTypeDadversedrugreactiontoLithiumcausesaTypeDadversedrugreactionbecauseitis:
    1. Animmunosuppressant
    2. Acarcinogen
    3. Ateratogen
    4. Anantiseizuremedication

ANS:C                      PTS:1

 

  1. ImmunomodulatorssuchasazathioprinemaycauseadelayedadversedrugreactionknownasaTypeDreactionbecausetheyareknown:
    1. Teratogens
    2. Carcinogens
    3. Tocausehypersensitivityreactions
    4. Hypothalamus-pituitary-adrenal(HPA)axissuppressants

ANS:B                      PTS:1

 

  1. A24-year-oldmalereceivedmultiplefracturesinamotorvehicleaccidentthatrequiredsignificantamountsofopioidmedicationtotreathisHeisatriskforType adversedrugreactionwhenhenolongerrequirestheopioids.
    1. A
    2. C
    3. E
    4. G

ANS:C                      PTS:1

 

  1. DrugsthatmaycauseaTypeEadversedrugreactioninclude:
    1. Betablockers
    2. Immunomodulators
    3. Antibiotics
    4. Oralcontraceptives

 

ANS:A                      PTS:1

 

  1. UnexpectedfailureofdrugtherapyisaType adversedrugreaction,commonlycausedby    .
    1. B;cytotoxichypersensitivity
    2. B;idiosyncraticresponse
    3. C;cumulativeeffectsofdrug
    4. F;drug-druginteraction

ANS:D                      PTS:1

 

  1. Clopidogreltreatmentfailuremayoccurwhenitisco-administeredwithomeprazole,knownasaType adversedrug
    1. A
    2. C
    3. E
    4. F

ANS:D                      PTS:1

 

Chapter6.PrinciplesofPharmacotherapyinOlderAdults

 

MULTIPLECHOICE

 

  1. Principlesofprescribingforolderadultsinclude:
A. Avoidingprescribinganynewerhigh-costmedications
B. Startingatalowdoseandincreasingthedoseslowly
C. Keepingtotaldoseatlowertherapeuticrange
D. Alloftheabove

 

ANS:B                      PTS:1

 

  1. Sadieisa90-year-oldpatientwhorequiresanewWhatchangesindrugdistributionwithagingwouldinfluenceprescribingforSadie?
A. Increasedvolumeofdistribution
B. Decreasedlipidsolubility
C. Decreasedplasmaproteins
D. Increasedmuscletofatratio

 

ANS:C                      PTS:1

 

  1. Glenisan82yearoldwhoneedstobeprescribedWhatchangesineliminationshouldbetakenintoconsiderationwhenprescribingforGlen?
A. IncreasedGFRwillrequirehigherdosesofsomerenallyexcreteddrugs
B. Decreasedtubularsecretionofmedicationwillrequiredosageadjustments
C. Thinskinwillcauseincreasedeliminationviasweat
D. Decreasedlungcapacitywillleadtomeasurabledecreasesinlungexcretionofdrugs

 

ANS:B                      PTS:1

 

  1. Amedicationreviewofanelderlyperson’smedicationsinvolves:

 

 

B. Havingthepatientbringalloftheirprescription,over-the-counter,andherbalmedicationtothevisit
C. Askingwhatotherprovidersarewritingprescriptionsforthem
D. Alloftheabove

 

ANS:D                      PTS:1

 

  1. Stepstoavoidpolypharmacyinclude:
A. Prescribingtwoorfewerdrugsfromeachdrugclass
B. Reviewingacompletedrughistoryevery12to18months
C. Encouragingtheelderlypatienttocoordinatetheircarewithalloftheirproviders
D. Evaluatingforduplicationsindrugtherapyanddiscontinuinganyduplications

 

ANS:D                      PTS:1

 

  1. Robertisa72yearoldwhohashypertensionandHeisatriskforcommonmedicationpracticesseenintheelderlyincluding:
A. Useofanotherperson’smedications
B. Hoardingmedications
C. Changinghismedicationregimenwithouttellinghisprovider
D. Alloftheabove

 

ANS:D                      PTS:1

 

  1. Toimprovepositiveoutcomeswhenprescribingfortheelderlythenursepractitionershould:
A. Assesscognitivefunctioningintheelder
B. Encouragethepatienttotakeaweekly“drugholiday”tokeepdrugcostsdown
C. Encouragethepatienttocutdrugsinhalfwithaknifetolowercosts
D. Alloftheabove

 

ANS:A                      PTS:1

 

 

  1. Whenanelderlydiabeticpatientisconstipatedthebesttreatmentoptionsinclude:
A. Mineraloil
B. Bulk-forminglaxativessuchaspsyllium
C. Stimulantlaxativessuchassenna
D. Stoolsoftenerssuchasdocusate

 

ANS:D                      PTS:1

 

  1. Deltaisan88yearoldwhohasmildWhatguidelinesshouldbefollowedwhenprescribingpainmanagementforDelta?
A. Keepthedoseofoxycodonelowtopreventdevelopmentoftolerance
B. Acetaminophenisthefirst-linedrugofchoice
C. AvoidprescribingNSAIDs
D. Addinashort-actingbenzodiazepineforasynergisticeffectonpain

 

ANS:B                      PTS:1

 

  1. RobertiscomplainingofpoorMedicationsthatmaycontributetosleepproblemsintheelderlyinclude:
A. Diuretics
B. Trazodone
C. Clonazepam
D. Levodopa

 

ANS:A                      PTS:1

 

Chapter 11.     ContactDermatitis

 

MULTIPLECHOICE

 

  1. Whenchoosingatopicalcorticosteroidcreamtotreatdiaperdermatitis,theidealmedicationwouldbe:
    1. Intermediatepotencycorticosteroidointment(Kenalog)
    2. Acombinationofacorticosteroidandanantifungal(Lotrisone)
    3. Alowpotencycorticosteroidcreamappliedsparingly(hydrocortisone1%)
    4. Ahighpotencycorticosteroidcream(DiproleneAF)

ANS:C                      PTS:1

 

  1. Topicalimmunomodulatorssuchaspimecrolimus(Elidel)ortacrolimus(Protopic)areusedfor:
    1. Short-termorintermittenttreatmentofatopicdermatitis
    2. Topicaltreatmentoffungalinfections(Candida)
    3. Chronic,inflammatoryseborrheicdermatitis
    4. Recalcitrantnodularacne

ANS:A                      PTS:1

 

  1. Long-termtreatmentofmoderateatopicdermatitisincludes:
    1. Topicalcorticosteroidsandemollients
    2. Topicalcorticosteroidsalone
    3. Topicalantipruritics
    4. Oralcorticosteroidsforexacerbationsofatopicdermatitis

ANS:A                      PTS:1

 

  1. Severecontactdermatitiscausedbypoisonivyorpoisonoakexposureoftenrequirestreatmentwith:
    1. Topicalantipruritics
    2. Oralcorticosteroidsfor2to3weeks
    3. Thicklyappliedtopicalintermediate-dosecorticosteroids
    4. Isolationofthepatienttopreventspreadofthedermatitis

ANS:B                      PTS:1

 

  1. Whenapatienthascontactdermatitis,wetdressingswithDomeborosolutionareusedfor:
    1. Cleaningtheweepingareaofdermatitis
    2. Bathingthepatienttopreventinfection
    3. Reliefofinflammation
    4. Providingabarrierlayertoprotectthesurroundingskin

ANS:C                      PTS:1

 

  • TopicalcorticosteroidsareusedtotreatseveralTopicalcorticosteroidsarecontraindicatedfortreatmentofwhichofthefollowingconditions?

 

a. Psoriasis c. Eczema
b. Contactdermatitis d. Rosacea

 

ANS:D                      PTS:1

 

  1. AtopicalcorticosteroidmaybeusedtoWhatinstructionmustbegiventoapatientforwhomatopicalcorticosteroidisprescribedfortreatmentoffacialeczema?
  2. “Becarefulnottogetanyofthemedicationinyour”
  3. “Stayoutofstrongsunlightwhileusingthe”
  4. “Putathinlayerofmedicationononceadayjustbeforeyougoto”
  5. “Checkbeforeyouuseitthatthemedicationislabeledfluorinated.”

ANS:A                      PTS:1

 

  1. GroupItopicalcorticosteroidsmaycauseadverseApatientwhoisbeingtreatedwithagroupItopicalcorticosteroidmustbecloselymonitoredfor

 

a. increasedhepaticenzymes. c. epithelialkeratopathy.
b. HPAsuppression. d. bonemarrowdepression.

ANS:B                      PTS:1

 

  1. Treatmentwithgentamicin(Garamycin)maypresentdisadvantagesfortheArenalpatient’suseofthedrugmayleadto
  2. deteriorationofthe
  3. riskofliverdamagesecondarytosystemic
  4. occurrenceof

ANS:D                      PTS:1

 

  1. Thetopicalantiviraldrugacyclovir(Zovirax)isusedtotreatseveraldifferentWhichofthefollowingconditionsisanunlabeleduseforacyclovir(Zovirax)?

 

a. Herpesgenitalis c. Herpeslabialis
b. HerpessimplexvirustypesIandII d. Epstein-Barrvirus

ANS:C                      PTS:1

 

  1. Lindane(Kwell,Scabene)isusedtotreatseveralForwhichdisorderistheuseoflindane(Kwell,Scabene)contraindicated?

 

a. Pediculosispubis c. Scabies
b. Sarcoptesscabiei d. Seizures

ANS:D                      PTS:1

 

 

 

 

  1. Scabiestreatmentfora4-year-oldchildincludesaprescriptionfor:
    1. Permethrin5%creamappliedfromtheneckdown
    2. Pyrethrinlotion
    3. Lindane1%shampoo
    4. Alloftheabove

ANS:A                      PTS:1

 

  1. VanessahasbeenHereducationwouldinclude:
    1. Sheshouldapplythescabiestreatmentcreamforanhourandwashitoff
    2. Scabiesmayneedtoberetreatedinaweekafterinitialtreatment
    3. Allmembersofthehouseholdandclosepersonalcontactsshouldbetreated
    4. Malathionisflammableandsheshouldtakecareuntilthesolutiondries

ANS:C                      PTS:1

 

  1. CatherinehasheadliceandhermotherisaskingaboutwhatproductsareavailablethatarenotTheonlynon-neurotoxinheadlicetreatmentis:
    1. Permethrin1%(Nix)
    2. Lindaneshampoo
    3. Malathion(Ovide)
    4. Benzoylalcohol(Ulesfia)

ANS:D                      PTS:1

 

 

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