Complete Test Bank With Answers
Sample Questions Posted Below
Chapter3.ImpactofDrugInteractionsandAdverseEventsonTherapeutics
MULTIPLECHOICE
- Whichofthefollowingpatientswouldbeathigherriskofexperiencingadversedrugreactions(ADRs):
- A32-year-oldmale
- A22-year-oldfemale
- A3-month-oldfemale
- A48-year-oldmale
ANS:C PTS:1
- InfantsandyoungchildrenareathigherriskofADRsdueto:
- Immaturerenalfunctioninschool-agechildren
- Lackofsafetyandefficacystudiesinthepediatricpopulation
- Children’sskinbeingthickerthanadults,requiringhigherdosagesoftopicalmedication
- Infantboyshavingahigherproportionofmusclemass,leadingtoahighervolumeofdistribution
ANS:B PTS:1
- TheelderlyareathighriskofADRsdueto:
- Havinggreatermusclemassthanyoungeradults,leadingtohighervolumeofdistribution
- Theextensivestudiesthathavebeenconductedondrugsafetyinthisagegroup
- Theblood-brainbarrierbeinglesspermeable,requiringhigherdosestoachievetherapeuticeffect
- Age-relateddecreaseinrenalfunction
ANS:D PTS:1
- Thetypeofadversedrugreactionthatistheresultofanunwantedbutotherwisenormalpharmacologicalactionofadruggivenintheusualtherapeuticdosesis
- TypeA
- TypeB
- TypeC
- TypeD
ANS:A PTS:1
- DigoxinmaycauseaTypeAadversedrugreactiondueto:
- Idiosyncraticeffects
- Itsnarrowtherapeuticindex
- Beingateratogen
- Beingacarcinogen
ANS:B PTS:1
- Changesintheindividualpharmacokineticparametersofadsorption,distribution,oreliminationmayresultinhighconcentrationsofthedruginthebody,leadingtowhichtypeofadversedrugreaction?
- TypeA
- TypeC
- TypeD
- TypeE
ANS:A PTS:1
- AccordingtotheWorldHealthOrganizationClassification,TypeBadversereactionsare:
- Whenadrugisateratogen
- Whenadrugiscarcinogenic
- AdelayedADR,suchasrenalfailure
- Anallergicoridiosyncraticresponse
ANS:D PTS:1
- SarahdevelopedarashafterusingatopicalThisisaType allergicdrugreaction.
- I
- II
- III
- IV
ANS:D PTS:1
- ApatientmaydevelopneutropeniafromusingtopicalSilvadeneNeutropeniaisa(n):
- Cytotoxichypersensitivityreaction
- Immunecomplexhypersensitivity
- Immediatehypersensitivityreaction
- Delayedhypersensitivityreaction
ANS:A PTS:1
- Anaphylacticshockisa:
- TypeIreaction,calledimmediatehypersensitivityreaction
- TypeIIreaction,calledcytotoxichypersensitivityreaction
- TypeIIIallergicreaction,calledimmunecomplexhypersensitivity
- TypeIVallergicreaction,calleddelayedhypersensitivityreaction
ANS:A PTS:1
- Jameshashypothalamic-pituitary-adrenalaxissuppressionfromchronicprednisone(acorticosteroid)Heisatriskforwhattypeofadversedrugreaction?
- TypeB
- TypeC
- TypeE
- TypeF
ANS:B PTS:1
- Thetreatmentforapatientwhoexperienceshypothalamic-pituitary-adrenalaxissuppressionwhiletakingthecorticosteroidprednisone,aTypeCadversedrugreaction,isto:
- Immediatelydiscontinuetheprednisone
- Administerepinephrine
- Slowlytaperthepatientoffoftheprednisone
- Monitorforlong-termeffects,suchascancer
ANS:C PTS:1
- TheACEinhibitorlisinoprilTeratogenscauseType adversedrugreaction.
- A
- B
- C
- D
ANS:D PTS:1
- CardiacdefectsareaknownTypeDadversedrugreactiontoLithiumcausesaTypeDadversedrugreactionbecauseitis:
- Animmunosuppressant
- Acarcinogen
- Ateratogen
- Anantiseizuremedication
ANS:C PTS:1
- ImmunomodulatorssuchasazathioprinemaycauseadelayedadversedrugreactionknownasaTypeDreactionbecausetheyareknown:
- Teratogens
- Carcinogens
- Tocausehypersensitivityreactions
- Hypothalamus-pituitary-adrenal(HPA)axissuppressants
ANS:B PTS:1
- A24-year-oldmalereceivedmultiplefracturesinamotorvehicleaccidentthatrequiredsignificantamountsofopioidmedicationtotreathisHeisatriskforType adversedrugreactionwhenhenolongerrequirestheopioids.
- A
- C
- E
- G
ANS:C PTS:1
- DrugsthatmaycauseaTypeEadversedrugreactioninclude:
- Betablockers
- Immunomodulators
- Antibiotics
- Oralcontraceptives
ANS:A PTS:1
- UnexpectedfailureofdrugtherapyisaType adversedrugreaction,commonlycausedby .
- B;cytotoxichypersensitivity
- B;idiosyncraticresponse
- C;cumulativeeffectsofdrug
- F;drug-druginteraction
ANS:D PTS:1
- Clopidogreltreatmentfailuremayoccurwhenitisco-administeredwithomeprazole,knownasaType adversedrug
- A
- C
- E
- F
ANS:D PTS:1
Chapter6.PrinciplesofPharmacotherapyinOlderAdults
MULTIPLECHOICE
- Principlesofprescribingforolderadultsinclude:
A. |
Avoidingprescribinganynewerhigh-costmedications |
B. |
Startingatalowdoseandincreasingthedoseslowly |
C. |
Keepingtotaldoseatlowertherapeuticrange |
D. |
Alloftheabove |
ANS:B PTS:1
- Sadieisa90-year-oldpatientwhorequiresanewWhatchangesindrugdistributionwithagingwouldinfluenceprescribingforSadie?
A. |
Increasedvolumeofdistribution |
B. |
Decreasedlipidsolubility |
C. |
Decreasedplasmaproteins |
D. |
Increasedmuscletofatratio |
ANS:C PTS:1
- Glenisan82yearoldwhoneedstobeprescribedWhatchangesineliminationshouldbetakenintoconsiderationwhenprescribingforGlen?
A. |
IncreasedGFRwillrequirehigherdosesofsomerenallyexcreteddrugs |
B. |
Decreasedtubularsecretionofmedicationwillrequiredosageadjustments |
C. |
Thinskinwillcauseincreasedeliminationviasweat |
D. |
Decreasedlungcapacitywillleadtomeasurabledecreasesinlungexcretionofdrugs |
ANS:B PTS:1
- Amedicationreviewofanelderlyperson’smedicationsinvolves:
B. |
Havingthepatientbringalloftheirprescription,over-the-counter,andherbalmedicationtothevisit |
C. |
Askingwhatotherprovidersarewritingprescriptionsforthem |
D. |
Alloftheabove |
ANS:D PTS:1
- Stepstoavoidpolypharmacyinclude:
A. |
Prescribingtwoorfewerdrugsfromeachdrugclass |
B. |
Reviewingacompletedrughistoryevery12to18months |
C. |
Encouragingtheelderlypatienttocoordinatetheircarewithalloftheirproviders |
D. |
Evaluatingforduplicationsindrugtherapyanddiscontinuinganyduplications |
ANS:D PTS:1
- Robertisa72yearoldwhohashypertensionandHeisatriskforcommonmedicationpracticesseenintheelderlyincluding:
A. |
Useofanotherperson’smedications |
B. |
Hoardingmedications |
C. |
Changinghismedicationregimenwithouttellinghisprovider |
D. |
Alloftheabove |
ANS:D PTS:1
- Toimprovepositiveoutcomeswhenprescribingfortheelderlythenursepractitionershould:
A. |
Assesscognitivefunctioningintheelder |
B. |
Encouragethepatienttotakeaweekly“drugholiday”tokeepdrugcostsdown |
C. |
Encouragethepatienttocutdrugsinhalfwithaknifetolowercosts |
D. |
Alloftheabove |
ANS:A PTS:1
- Whenanelderlydiabeticpatientisconstipatedthebesttreatmentoptionsinclude:
A. |
Mineraloil |
B. |
Bulk-forminglaxativessuchaspsyllium |
C. |
Stimulantlaxativessuchassenna |
D. |
Stoolsoftenerssuchasdocusate |
ANS:D PTS:1
- Deltaisan88yearoldwhohasmildWhatguidelinesshouldbefollowedwhenprescribingpainmanagementforDelta?
A. |
Keepthedoseofoxycodonelowtopreventdevelopmentoftolerance |
B. |
Acetaminophenisthefirst-linedrugofchoice |
C. |
AvoidprescribingNSAIDs |
D. |
Addinashort-actingbenzodiazepineforasynergisticeffectonpain |
ANS:B PTS:1
- RobertiscomplainingofpoorMedicationsthatmaycontributetosleepproblemsintheelderlyinclude:
A. |
Diuretics |
B. |
Trazodone |
C. |
Clonazepam |
D. |
Levodopa |
ANS:A PTS:1
Chapter 11. ContactDermatitis
MULTIPLECHOICE
- Whenchoosingatopicalcorticosteroidcreamtotreatdiaperdermatitis,theidealmedicationwouldbe:
- Intermediatepotencycorticosteroidointment(Kenalog)
- Acombinationofacorticosteroidandanantifungal(Lotrisone)
- Alowpotencycorticosteroidcreamappliedsparingly(hydrocortisone1%)
- Ahighpotencycorticosteroidcream(DiproleneAF)
ANS:C PTS:1
- Topicalimmunomodulatorssuchaspimecrolimus(Elidel)ortacrolimus(Protopic)areusedfor:
- Short-termorintermittenttreatmentofatopicdermatitis
- Topicaltreatmentoffungalinfections(Candida)
- Chronic,inflammatoryseborrheicdermatitis
- Recalcitrantnodularacne
ANS:A PTS:1
- Long-termtreatmentofmoderateatopicdermatitisincludes:
- Topicalcorticosteroidsandemollients
- Topicalcorticosteroidsalone
- Topicalantipruritics
- Oralcorticosteroidsforexacerbationsofatopicdermatitis
ANS:A PTS:1
- Severecontactdermatitiscausedbypoisonivyorpoisonoakexposureoftenrequirestreatmentwith:
- Topicalantipruritics
- Oralcorticosteroidsfor2to3weeks
- Thicklyappliedtopicalintermediate-dosecorticosteroids
- Isolationofthepatienttopreventspreadofthedermatitis
ANS:B PTS:1
- Whenapatienthascontactdermatitis,wetdressingswithDomeborosolutionareusedfor:
- Cleaningtheweepingareaofdermatitis
- Bathingthepatienttopreventinfection
- Reliefofinflammation
- Providingabarrierlayertoprotectthesurroundingskin
ANS:C PTS:1
- TopicalcorticosteroidsareusedtotreatseveralTopicalcorticosteroidsarecontraindicatedfortreatmentofwhichofthefollowingconditions?
a. |
Psoriasis |
c. |
Eczema |
b. |
Contactdermatitis |
d. |
Rosacea |
ANS:D PTS:1
- AtopicalcorticosteroidmaybeusedtoWhatinstructionmustbegiventoapatientforwhomatopicalcorticosteroidisprescribedfortreatmentoffacialeczema?
- “Becarefulnottogetanyofthemedicationinyour”
- “Stayoutofstrongsunlightwhileusingthe”
- “Putathinlayerofmedicationononceadayjustbeforeyougoto”
- “Checkbeforeyouuseitthatthemedicationislabeledfluorinated.”
ANS:A PTS:1
- GroupItopicalcorticosteroidsmaycauseadverseApatientwhoisbeingtreatedwithagroupItopicalcorticosteroidmustbecloselymonitoredfor
a. |
increasedhepaticenzymes. |
c. |
epithelialkeratopathy. |
b. |
HPAsuppression. |
d. |
bonemarrowdepression. |
ANS:B PTS:1
- Treatmentwithgentamicin(Garamycin)maypresentdisadvantagesfortheArenalpatient’suseofthedrugmayleadto
- deteriorationofthe
- riskofliverdamagesecondarytosystemic
- occurrenceof
ANS:D PTS:1
- Thetopicalantiviraldrugacyclovir(Zovirax)isusedtotreatseveraldifferentWhichofthefollowingconditionsisanunlabeleduseforacyclovir(Zovirax)?
a. |
Herpesgenitalis |
c. |
Herpeslabialis |
b. |
HerpessimplexvirustypesIandII |
d. |
Epstein-Barrvirus |
ANS:C PTS:1
- Lindane(Kwell,Scabene)isusedtotreatseveralForwhichdisorderistheuseoflindane(Kwell,Scabene)contraindicated?
a. |
Pediculosispubis |
c. |
Scabies |
b. |
Sarcoptesscabiei |
d. |
Seizures |
ANS:D PTS:1
- Scabiestreatmentfora4-year-oldchildincludesaprescriptionfor:
- Permethrin5%creamappliedfromtheneckdown
- Pyrethrinlotion
- Lindane1%shampoo
- Alloftheabove
ANS:A PTS:1
- VanessahasbeenHereducationwouldinclude:
- Sheshouldapplythescabiestreatmentcreamforanhourandwashitoff
- Scabiesmayneedtoberetreatedinaweekafterinitialtreatment
- Allmembersofthehouseholdandclosepersonalcontactsshouldbetreated
- Malathionisflammableandsheshouldtakecareuntilthesolutiondries
ANS:C PTS:1
- CatherinehasheadliceandhermotherisaskingaboutwhatproductsareavailablethatarenotTheonlynon-neurotoxinheadlicetreatmentis:
- Permethrin1%(Nix)
- Lindaneshampoo
- Malathion(Ovide)
- Benzoylalcohol(Ulesfia)
ANS:D PTS:1
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