Chapter 8 Drug Therapy for Dyslipidemia


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Chapter 8  Drug Therapy for Dyslipidemia



Complete chapter Questions And Answers

Sample Questions



1. An obese patient who has an elevated triglyceride level and reduced high-density lipoprotein cholesterol is seen by her primary care physician. What do these data suggest in this patient?

  1. A)  The development of arthritic syndrome
  2. B)  The development of metabolic syndrome
  3. C)  The development of Reye’s syndrome
  4. D)  The development of Tay-Sachs disease

Ans: B


Metabolic syndrome is noted when the patient has elevated waist circumference, elevated triglycerides, reduced high-density lipoprotein cholesterol, elevated blood pressure, and elevated fasting glucose. Elevated triglyceride level and reduced high-density lipoprotein cholesterol are not indicative of arthritic syndrome. Reye’s syndrome is marked by acute encephalopathy and seen in children under the age of 15 years after an acute viral infection. Tay-Sachs is a genetic disease characterized by neurological deterioration in the first year of life.

2. A patient has an elevated total serum cholesterol of 260 mg/dL. Which of the following aspects of patient teaching of lifestyle changes is most important for the patient?

  1. A)  Eat organic foods.
  2. B)  Stop smoking.
  3. C)  Increase rest periods.
  4. D)  Drink whole milk.

Ans: B Feedback:

Therapeutic lifestyle changes to lower serum cholesterol, including exercise, smoking cessation, change in diet, and drug therapy, are recommended to lower serum cholesterol. The patient with an elevated serum cholesterol should increase exercise and not increase rest periods. The patient should consume low-fat dairy products and avoid whole milk. Organic foods are not specifically recommended.

3. A patient with a diagnosis of cardiovascular disease is taking atorvastatin calcium (Lipitor) to reduce serum cholesterol. What is the goal of therapy for LDL cholesterol for a patient taking atorvastatin calcium (Lipitor)?

  1. A)  100 to 115 mg/dL
  2. B)  75 to 85 mg/dL
  3. C)  Less than 60 mg/dL
  4. D)  Less than 100 mg/dL

Ans: D
In patients with a diagnosis of cardiovascular disease, the goal of therapy is an LDL below 100 mg/dL.

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4. A male patient is taking atorvastatin calcium (Lipitor) to reduce serum cholesterol. Which of the following aspects of patient teaching is most important?

  1. A)  Call his physician if he develops muscle pain.
  2. B)  It is unacceptable to eat dietary fats.
  3. C)  Decrease the dose if lethargy occurs.
  4. D)  Eat two eggs per day to increase protein stores.

Ans: A
Patients should be advised to notify their health care provider if unexplained muscle pain or tenderness occurs. The patient should avoid saturated fats when taking statins but should not entirely eliminate fats from his diet. The patient should not decrease the dose of statins without the physician’s knowledge. The patient should not increase the intake of eggs due to the increase in cholesterol.

5. A patient has begun taking cholestyramine. Which of the following are noted as the most common adverse effects?

  1. A)  Nausea, flatulence, and constipation
  2. B)  Increased appetite and blood pressure
  3. C)  Fatigue and mental disorientation
  4. D)  Hiccups, nasal congestion, and dizziness

Ans: A
Cholestyramine is not absorbed systemically, so the main adverse effects are gastrointestinal (GI) ones (abdominal fullness, flatulence, diarrhea, and constipation). Constipation is especially common, and a bowel program may be necessary to control this problem.

6. A patient who has been taking a statin has seen an improvement in his cholesterol laboratory values; however, the low-density lipoprotein remains elevated. What medication will be added to the medication regimen?

  1. A)  Digoxin (Lanoxin)
  2. B)  Vitamin D
  3. C)  Cholestyramine (Questran)
  4. D)  Calcium carbonate

Ans: C
Cholestyramine is administered to patients to reduce LDL cholesterol in patients who are already taking a statin drug. Digoxin is not given to lower LDL cholesterol. Vitamin D is not given to lower LDL cholesterol. Calcium carbonate is not given to lower LDL cholesterol.

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