Chapter 57  Drugs Affecting Gastrointestinal Secretions

Chapter 57  Drugs Affecting Gastrointestinal Secretions

Complete Chapter Questions And Answers
 

Sample Questions

1. What action does the histamine-2 antagonist administered by the nurse have on the human body that
will help to prevent peptic ulcer disease?

A) Destroys Helicobacter pylori

B) Coats and protects the stomach lining

C) Increases the pH of the secreted hydrochloric acid

D) Reduces the amount of hydrochloric acid secreted

Ans: D

Feedback:

Histamine-2 antagonists are administered to reduce the amount of hydrochloric acid secreted in the
stomach, which helps to prevent peptic ulcer disease. H2 antagonists do not act as an antibiotic to kill
bacteria (i.e., H. pylori) coat and protect the stomach lining like sucralfate (Carafate), or increase the
pH of the secreted hydrochloric acid.

2. What classification of drugs does the nurse administer to treat peptic ulcers by suppressing the
secretion of hydrochloric acid into the lumen of the stomach?

A) Antipeptic agents

B) Histamine-2 antagonists

C) Proton pump inhibitors

D) Prostaglandins

Ans: C

Feedback:

Proton pump inhibitors suppress the secretion of hydrochloric acid into the lumen of the stomach.
Antipeptic agents coat any injured area in the stomach to prevent further injury. H2 antagonists block
the release of hydrochloric acid in response to gastrin. Prostaglandins inhibit secretion of gastrin and
increase secretion of the mucous lining of the stomach.

3. The nurse is caring for a patient requiring digestive enzyme replacement therapy and establishes what

Test Bank – Focus on Nursing Pharmacology (7th Edition by Amy Karch) 932

appropriate nursing diagnosis for this patient?

A) Acute pain

B) Risk for constipation

C) Risk for imbalanced nutrition

D) Bowel incontinence

Ans: C

Feedback:

The nurse would be concerned about the patient’s nutritional status because lack of digestive enzymes
results in malnutrition. Replacement digestive enzymes help the patient improve digestion and
absorption of essential nutrients. Effectiveness of the therapy is determined by the patient’s ability to
maintain balanced nutrition. The other three options are not applicable to the use of replacement
digestive enzymes.

4. What nursing interventions are included in the plan of care for a patient receiving antacids to relieve GI
discomfort?

A) Administer this drug with other drugs or food.

B) Administer the antacid 1 hour before or 2 hours after other oral medications.

C) Limit fluid intake to decrease dilution of the medication in the stomach.

D) Have the patient swallow the antacid whole and do not crush or chew the tablet.

Ans: B

Feedback:

A patient taking antacids should be advised to take the antacid 1 hour before or 2 hours after other oral
medications. These tablets are often chewed to increase effectiveness. Limiting fluid intake can result
in rebound fluid retention so that patients should be encouraged to maintain hydration. It is not
necessary to take an antacid with other drugs, nor with food.

5. An adult patient is prescribed cimetidine (Tagamet). A nurse will instruct the patient that an appropriate
dosage and frequency of cimetidine is what?

A) 20 mg PO b.i.d

B) 150 mg PO b.i.d

C) 300 mg PO at bedtime

D) 800 mg PO at bedtime

Ans: D

Feedback:

An appropriate dosage and frequency for cimetidine is 800 mg PO at bedtime. Also, 300 mg can be
taken q.i.d at meals and at bedtime. Ranitidine is taken 150 mg daily or b.i.d. Famotidine is taken 20
mg PO b.i.d. Nizatidine can be taken 150 to 300 mg PO at bedtime.