Chapter 46 Drug Therapy for Myasthenia Gravis and Alzheimer’s Disease

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Chapter 46  Drug Therapy for Myasthenia Gravis and Alzheimer’s Disease

 

 

Complete chapter Questions And Answers
 

Sample Questions

 

 

1. A patient has atony of the smooth muscle of the gastrointestinal tract. Which type of medication may be administered to increase smooth muscle strength?

  1. A)  Anticholinergic drugs
  2. B)  Cholinergic drugs
  3. C)  Muscle relaxants
  4. D)  Selective serotonin reuptake inhibitors

Ans: B
Feedback:
Cholinergic drugs are used to treat atony of the smooth muscle of the gastrointestinal tract and urinary systems. Anticholinergic agents will decrease muscle strength. Muscle relaxants will decrease muscle strength. Selective serotonin reuptake inhibitors are not used for atony of the smooth muscle of the gastrointestinal tract.

2. A patient is diagnosed with Alzheimer’s disease. The nurse should anticipate administering which of the following medications?

  1. A)  Bethanechol (Urecholine)
  2. B)  Neostigmine (Prostigmin)
  3. C)  Donepezil (Aricept)
  4. D)  Physostigmine salicylate (Antilirium)

Ans: C
Feedback:
Donepezil (Aricept) is used to treat mild to moderate Alzheimer’s disease. Bethanechol (Urecholine) produces smooth muscle contractions and is not used to treat Alzheimer’s disease. Neostigmine (Prostigmin) is not used to treat Alzheimer’s disease; it is used to treat myasthenia gravis. Physostigmine is not used to treat Alzheimer’s disease; it is an antidote for overdose of anticholinergic drugs.

3. A patient with myasthenia gravis is administered neostigmine (Prostigmin). How does this drug produce its therapeutic effect?

  1. A)  It stimulates the sympathetic nervous system.
  2. B)  It stimulates the parasympathetic nervous system.
  3. C)  It stimulates the cardiac smooth muscle.
  4. D)  It stimulates the respiratory system.

Ans: B Feedback:

Neostigmine (Prostigmin) stimulates the parasympathetic nervous system. It does not stimulate the sympathetic nervous system, cardiac system, or respiratory system.

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4. A patient is administered edrophonium (Tensilon) to confirm the diagnosis of myasthenia gravis. What effect will the edrophonium (Tensilon) have 30 minutes after the medication administration, which will confirm the diagnosis?

  1. A)  Improved breathing
  2. B)  Decreased fatigue
  3. C)  Decreased muscle spasms
  4. D)  Increased urinary output

Ans: A
Feedback:
Edrophonium (Tensilon) is used to diagnose myasthenia gravis. After administration, it will improve breathing in patients who have myasthenia gravis. Edrophonium will not decrease fatigue. Edrophonium will not decrease muscle spasms or increase urinary output.

  1. A patient with myasthenia gravis is administered pyridostigmine (Mestinon) for the first time. She asks the nurse the reason why she has been changed to this medication. Which of the following is the nurse’s best response?
    1. A)  “Pyridostigmine (Mestinon) will allow you to awaken with the ability to

      swallow.”

    2. B)  “Pyridostigmine (Mestinon) can be taken every other day.”
    3. C)  “Pyridostigmine (Mestinon) is a faster-release form of cholinergic agent.”
    4. D)  “Pyridostigmine (Mestinon) is taken one time per day for better control.”

    Ans: A
    Feedback:
    Pyridostigmine is a slow-release form that is taken at bedtime and allows the patient the ability to swallow in the morning. Pyridostigmine is usually taken two times per day, not every other day. Pyridostigmine is a slow-release form, not a fast-release form. Pyridostigmine is taken two times per day, not one time per day.

  2. A patient is diagnosed with a paralytic ileus. Which of the following medications will be administered to treat a paralytic ileus?
    1. A)  Neostigmine (Prostigmin)
    2. B)  Donepezil (Aricept)
    3. C)  Bethanechol (Urecholine)
    4. D)  Ambenonium (Mytelase)

Ans: C Feedback:

Bethanechol (Urecholine) produces smooth muscle contractions and is used for obstructive conditions of the gastrointestinal tract. Neostigmine is used to treat myasthenia gravis. Donepezil is used to treat Alzheimer’s disease. Ambenonium is used to treat myasthenia gravis.

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