Chapter 44 Drugs Used for Cancer Treatment

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Chapter 44  Drugs Used for Cancer Treatment

 

 

Complete Chapter Questions And Answers
 

Sample Questions

 

MULTIPLE CHOICE

1. The nurse is educating a patient with cancer about combination chemotherapy. Which is an accurate statement?
A.
“Combination chemotherapy is the administration of an antineoplastic drug that will be toxic during a specific phase of cellular growth.”
B.
“Combination chemotherapy is the administration of an antineoplastic drug that is active throughout the cell cycle.”
C.
“Combination chemotherapy is the administration of antineoplastic drugs that change the way the body responds to cancer or strengthens the immune system.”
D.
“Combination chemotherapy is the administration of antineoplastic drugs, which results in cell death during different phases of the cell cycle.”

ANS: D

Feedback
A
This is a single drug regimen, not a combination.
B
This is a single drug regimen, not a combination.
C
This is a single drug regimen, not a combination.
D
Use of combination drug therapy is superior in therapeutic effect to the use of single-agent chemotherapy.

DIF: Cognitive Level: Comprehension REF: 697
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity

2. The cell cycle–specific agent vincristine sulphate (Oncovin) acts in which phase of the cell’s life cycle?
A.
S phase
B.
Mitotic phase
C.
Phase G1
D.
Phase G0

ANS: B

Feedback
A
The S phase is the stage of active synthesis of two sets of DNA.
B
Vinca alkaloids block the formation of the mitotic spindle during mitosis, thus inhibiting cell division.
C
Phase G1 is considered a presynthetic phase in which the cell prepares for DNA synthesis by manufacturing necessary enzymes.
D
G0 is the largest variable in the cell cycle and, during this resting phase, the cell is not actively replicating.

DIF: Cognitive Level: Knowledge REF: 705
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity

3. What is the importance of correlating the dosage schedule with cell cycle–specific drug therapy?
A.
Ongoing proliferation of neoplastic tissue
B.
The known cellular kinetics of the neoplasm
C.
The hormonal requirements of the patient
D.
The body’s response in strengthening the immune system

ANS: B

Feedback
A
The object of chemotherapy is to stop the proliferation of neoplastic tissue.
B
Cell cycle–specific agent scheduling should be correlated with the known cellular kinetics of the particular type of neoplasm being treated. This type of drug is schedule-dependent and selectively toxic when the cell is in a specific phase of growth.
C
Hormones are only used in specific types of cancer and are not related to cell cycle specificity.
D
Immunomodulators are used to enhance the body’s response in strengthening the immune system.

DIF: Cognitive Level: Comprehension REF: 689
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity

4. When are cancer cells most sensitive to chemotherapy?
A.
Resting phases
B.
Rapid division
C.
Remission intervals
D.
Slow replication

ANS: B

Feedback
A
Cancer cells are not sensitive to chemotherapy during resting phases.
B
The cancer cells are the most sensitive to chemotherapy when the cells are dividing rapidly.
C
Cancer cells are not sensitive to chemotherapy during remission intervals.
D
Cancer cells are not sensitive to chemotherapy during slow replication.

DIF: Cognitive Level: Knowledge REF: 697
TOP: Nursing Process Step: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity

 

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