Chapter 32 Airway Pharmacology

Chapter 32  Airway Pharmacology

Complete Chapter Questions And Answers
 

Sample Questions

MULTIPLE CHOICE

1. Which of the following phases constitute the course of drug action from dose to effect?
1. drug administration
2. pharmacognosy
3. pharmacokinetic
4. pharmacodynamic
a.
1, 2, and 3
b.
1, 3, and 4
c.
2, 3, and 4
d.
1, 2, 3, and 4

ANS: B
Three phases constitute the course of drug action from dose to effect: the drug administration, pharmacokinetic, and pharmacodynamic phases.

DIF: Recall REF: p. 708 OBJ: 1

2. Which of the following devices are most commonly used to deliver aerosols by the inhalation route?
1. dry powder inhaler
2. metered dose inhaler
3. small-volume nebulizer
4. slip-stream nebulizer
a.
1 and 3
b.
2 and 4
c.
1, 2, and 3
d.
1, 2, 3, and 4

ANS: C
The most commonly used devices to administer orally or nasally inhaled aerosols are the metered-dose inhaler, the small-volume nebulizer, and the dry-powder inhaler.

DIF: Recall REF: p. 708 OBJ: 1

3. Which one or more of the following devices is NOT used in combination with metered dose inhaler (MDI) therapy to reduce the need for hand-breathing coordination and oropharyngeal impaction of aerosolized drugs?
a.
nonvalved spacer devices
b.
one-way spacer
c.
holding chambers
d.
drying chambers

ANS: D
Reservoir devices, including both holding chambers with one-way inspiratory valves and simple, nonvalved spacer devices, are often added to an MDI to reduce the need for complex hand-breathing coordination and to reduce oropharyngeal impaction of the aerosol drug.

DIF: Recall REF: p. 708 OBJ: 1

4. Which of the following is NOT an advantage for the treatment of the respiratory tract with inhaled aerosols?
a.
Doses are usually smaller.
b.
Onset of drug action is rapid.
c.
Delivered dose is consistent with each administration.
d.
Systemic side effects are often fewer and less severe.

ANS: C
The advantages for treatment of the respiratory tract with inhaled aerosols are as follows:
• Aerosol doses are usually smaller than doses for systemic administration.
• Onset of drug action is rapid.
• Delivery is targeted to the organ requiring treatment.
• Systemic side effects are often fewer and less severe.

DIF: Recall REF: p. 708 OBJ: 1

5. Which phase describes the time course and disposition of a drug in the body based on its absorption, distribution, metabolism, and elimination?
a.
pharmaceutical
b.
pharmacognosy
c.
pharmacokinetic
d.
pharmacodynamic

ANS: C
The pharmacokinetic phase of drug action describes the time course and disposition of a drug in the body based on its absorption, distribution, metabolism, and elimination.

DIF: Recall REF: p. 708 OBJ: 1